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The opioid epidemic in the United States continues to evolve, with each new wave bringing substances more powerful and dangerous than the last. One of the latest threats is 7-hydroxymitragynine (7-OH), a semi-synthetic opioid derived from the kratom plant. While kratom has been used in its natural form for centuries, 7-OH is far more potent, as laboratory studies indicate it can be 13 times stronger than morphine.
For nearly two years, 7-OH products were sold openly in convenience stores, smoke shops, and online retailers across Florida and other states. They were marketed under the label of “kratom alkaloids” or “kratom-enhanced” products, often without adequate warnings of their addictive potential. Many unsuspecting users believed they were purchasing natural kratom alternatives, when in reality they were consuming a powerful opioid with no approved medical use and no human safety studies.
The consequences have been alarming. Emergency calls related to 7-OH exposures have surged, reports of severe addiction are mounting, and families are beginning to connect overdoses and wrongful deaths to the unregulated sale of these products. In August 2025, Florida moved to classify 7-OH as a Schedule I substance, placing it in the same category as heroin due to its high potential for abuse and lack of medical benefit.
This sudden regulatory action leaves behind an important question: What about the thousands of people already harmed by 7-OH addiction and overdose? Victims and their families may now have legal rights to pursue lawsuits against manufacturers, distributors, and retailers that profited from selling this dangerous drug.
7-OH is not kratom, although it is often marketed as if it were. Instead, it is a semi-synthetic opioid created by extracting mitragynine (the main active alkaloid in kratom) and oxidizing it into 7-OH. By the time this process is complete, the product is no longer a natural supplement; it is a pure opioid compound.
Laboratory testing has shown that animals cannot distinguish between 7-OH, fentanyl, and morphine. In other words, its effects mirror those of highly addictive and deadly opioids already driving the overdose epidemic. Despite this, no clinical studies in humans have been conducted to determine safe dosage, long-term effects, or risk profiles.
For consumers, this means products labeled as kratom shots, gummies, or capsules may actually contain high concentrations of 7-OH, exposing users to addiction and overdose risks far beyond what they anticipated. Many people who thought they were buying a natural energy booster or recovery aid instead developed full-scale opioid dependence.
Florida’s emergency ban on 7-OH came after a sharp increase in medical emergencies tied to the drug. According to the National Drug Early Warning System, between January 2023 and April 2025, there were over 4,200 emergency service calls related to kratom and 7-OH overdoses, with numbers continuing to rise. Florida Poison Control also reported 191 specific 7-OH exposure calls, marking a significant upward trend.
Officials determined that 7-OH posed too great a threat to remain on the shelves. On August 13, 2025, the state placed 7-OH on its Schedule I list, classifying it alongside heroin and other opioids with no recognized medical value.
The FDA has also recommended that the DEA classify 7-OH as a federally controlled substance. If adopted, this would make possession, distribution, or sale of 7-OH illegal nationwide. Until that occurs, state-level bans like Florida’s are the strongest measure to curb its availability.
The move was prompted not only by overdose calls but also by reports of severe withdrawal syndromes, dependency issues, and cases of young people being targeted with mislabeled kratom-enhanced products. Officials believe that without regulation, thousands more individuals could fall victim to addiction or even death.
The effects of 7-OH mirror those of other opioids: relaxation, sedation, euphoria, and pain relief. However, its potency makes it extremely dangerous when misused.
Addiction Risks
Users report developing a dependence on 7-OH much more quickly than with kratom or prescription opioids. Online forums dedicated to recovery are filled with accounts of individuals unable to stop using, even after experiencing severe withdrawal symptoms such as nausea, tremors, sweating, anxiety, and insomnia.
Some people began using 7-OH believing it could help them taper off other opioids, only to find themselves locked in a more intense cycle of addiction.
Overdose Risks
Because products containing 7-OH are unregulated, users often have no way of knowing how much of the substance they are consuming. Too much 7-OH can suppress breathing, a condition known as respiratory depression, which is the leading cause of opioid overdose deaths.
Medical professionals warn that naloxone (Narcan) can reverse a 7-OH overdose in most cases, but the rising number of emergency calls suggests that overdoses are occurring frequently and are life-threatening.
Victims of 7-OH addiction and overdose may be eligible to file lawsuits against the companies that manufactured, marketed, and sold these dangerous products. Potential claims include:
Because many of these products were marketed as “kratom alternatives” and sold in gas stations and convenience stores, victims often had no idea they were consuming a Schedule I-level opioid. This deception could serve as the foundation of strong legal claims.
While Florida has taken action, 7-OH products have been distributed across the country. Companies based in multiple states have sold kratom-enhanced drinks, gummies, and tablets that were later found to contain only 7-OH.
This means potential lawsuits are not limited to Florida. Victims in states without bans may still pursue claims if they suffered addiction, overdose, or death after using these products. As federal regulators move closer to classifying 7-OH as illegal, the scope of liability for manufacturers and distributors is likely to expand nationwide.
The opioid epidemic has shown that when dangerous drugs are allowed to flood the market without proper warnings or regulation, the consequences are devastating. Legal action is one of the most effective tools available to hold companies accountable and compensate victims.
For individuals struggling with 7-OH addiction, lawsuits can provide resources for rehabilitation, medical treatment, and long-term recovery support. For families of overdose victims, wrongful death claims can bring financial relief for funeral costs, lost income, and emotional suffering.
Just as litigation against opioid manufacturers and distributors has exposed deceptive practices in the past, 7-OH lawsuits could play a critical role in preventing future harm and forcing transparency in how emerging substances are marketed.
If you or someone you love has suffered addiction, overdose, or wrongful death linked to 7-OH products, you are not alone. Parker Waichman LLP is a national law firm representing victims of dangerous drugs and defective products. Our product injury lawsuit attorneys are currently investigating cases involving 7-OH and its link to severe addiction and overdose fatalities.
Call 1-800-YOUR-LAWYER (1-800-968-7529) today for a free and confidential consultation. We will review your case, explain your legal options, and fight to hold those responsible accountable. Regardless of your location or where your injury occurred, our nationwide product injury law firm is ready to assist you.
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